Selank (TP-7)
Selank acetate, Thr-Lys-Pro-Arg-Pro-Gly-Pro, TKPRPGP
Forms: Nasal drops (the form registered in Russia), gray-market nasal sprays and injectable 'research' powder; also sold as a 'supplement' in some markets.
A synthetic seven-amino-acid analogue of the peptide tuftsin (Thr-Lys-Pro-Arg-Pro-Gly-Pro). Registered in Russia as an anti-anxiety drug; not approved in most other countries and sold online.
Legal status: A medicine in Russia; in most countries unapproved, sold as a 'research' peptide or even a supplement; varies by country. Not named on the WADA List; tested athletes should check.
What it gives
What people use it for and what the sources report. Strength is a general category from the literature: mild, clear or strong.
Purpose
Taken for calm focus and stress control, often together with Semax. Russian studies in anxiety disorders reported an anti-anxiety effect; US pharmacologists describe it as poorly studied. Benefits for athletes are unproven.
What people seek and what studies show
People hope for less anxiety without sedation and clearer thinking under pressure. In lab studies it modulated GABA receptors, the system benzodiazepines act on, and in rats it strengthened diazepam's anti-anxiety effect. A Russian comparison with phenazepam in 60 patients with anxiety-related disorders reported a clear anti-anxiety effect, but independent controlled trials are lacking.
Effects
Evidence: Limited human data — some human studies, small or short
Sought effects by goal (as reported)
Possible side effects
Possible does not mean certain: whether they appear depends on dose, duration, individual response and monitoring. Below — what to watch for and how to notice it early.
3 possible side effects
level · how often it is reportedWhat the levels mean
Level: general category from the literature, not your personal risk
How often
- common
- reported often
- possible
- reported in some people
- rare
- reported occasionally
How to lower the risks
General ways to lower the chance of each side effect. No measure removes a risk completely.
Products obtained without a prescription are often fake, mislabeled or non-sterile, and there is no way to check at home. For legal supplements, look for third-party testing (Informed Sport, NSF).
What is unknown cannot be lowered, only avoided; tell your doctor what you have taken.
Low-level side effects
Check-ups and blood tests
Which tests and check-ups to do and when. This is a guide — agree the exact schedule with your doctor.
Which doctors can help
For women
The Russian label lists pregnancy and breastfeeding as contraindications.
Myth & fact
“Selank is a mild natural calmer, so it is safe to mix with anything.”
It acts on the GABA system, as benzodiazepines do, and boosted diazepam in rats; combinations with alcohol or sedatives have not been studied in people.
Combinations
No specific combination notes for this substance yet. The stack check still adds up side effects that several substances share.
Sources
Possible side effects by body system, combinations, how to lower the risks and which tests to do — free.
Open the stack check