AOD-9604 (HGH fragment 176-191)

AOD9604, HGH Frag 176-191, Frag 176-191, hGH 176-191, Human growth hormone fragment 176-191

Forms: 'HGH Frag 176-191' is essentially the same peptide: AOD-9604 is hGH 177–191 with a tyrosine added at the start.

PeptidesNot approved for humansWADA S2 · prohibitedEvidence: limited human data

A modified fragment from the tail end of the growth hormone molecule, designed as a fat-loss drug without GH's growth effects. It failed its obesity trials and was never approved.

What it gives

What people use it for and what the sources report. Strength is a general category from the literature: mild, clear or strong.

Purpose

Used for fat loss, especially 'stubborn' fat, and sometimes for joints. In human trials (mostly of tablets) it was well tolerated but gave no meaningful weight loss; it does not raise IGF-1 and has no anabolic effect. Joint claims rest on animal data.

What people seek and what studies show

People hope to lose fat, especially at the waist, without growth hormone's effects on blood sugar, water retention or IGF-1. In obese mice it increased fat breakdown and slowed weight gain without raising blood sugar. In people, small studies saw only brief, modest changes; the main obesity trial failed, and its results were announced by the company rather than published. Cartilage repair is shown only in rabbits.

Effects

Fat loss

Evidence: Limited human data — some human studies, small or short

Sought effects by goal (as reported)

Cutting
Sought for: fat loss
Recomposition
Sought for: fat loss
Endurance
Sought for: fat loss

Possible side effects

Possible does not mean certain: whether they appear depends on dose, duration, individual response and monitoring. Below — what to watch for and how to notice it early.

3 possible side effects

level · how often it is reported
Elevated
Black-market quality risk (fakes, contamination)
Unregulated 'research' powder: content, purity and sterility are not controlled.
How to notice: Unexpected effects, pain or infection, a stronger or weaker effect than expected.
common
Moderate
Unknown long-term safety (little human data)
Trials were short; the FDA notes possible immune reactions and serious adverse events with an unclear causal link, so long-term safety is unknown.
How to notice: Nothing to notice — the risk is what is not yet known.
possible
Low
Injection pain, infection, oil cough
Pain, redness or infection where injected; human trials mainly tested a tablet form, so injected use is barely studied.
How to notice: Soreness, lumps; a short coughing fit right after an injection.
possible

What the levels mean

Lowbackground — just be aware
Moderatewatch for signs
Elevatedneeds regular control
Highcritical — can be life-threatening or permanent

Level: general category from the literature, not your personal risk

How often

common
reported often
possible
reported in some people
rare
reported occasionally

How to lower the risks

General ways to lower the chance of each side effect. No measure removes a risk completely.

ElevatedBlack-market quality risk (fakes, contamination)

Products obtained without a prescription are often fake, mislabeled or non-sterile, and there is no way to check at home. For legal supplements, look for third-party testing (Informed Sport, NSF).

ModerateUnknown long-term safety (little human data)

What is unknown cannot be lowered, only avoided; tell your doctor what you have taken.

Low-level side effects

Injection site
Sterile technique, never share needles, vials or pens; see a doctor for a hot, swollen site. If equipment was ever shared, test for HIV and hepatitis B/C and ask about hepatitis B vaccination.

Check-ups and blood tests

Which tests and check-ups to do and when. This is a guide — agree the exact schedule with your doctor.

The sources list no specific tests for this substance on its own. Together with other substances, the stack check shows the tests for the whole combination.

Which doctors can help

Sports physiciancoordinates everything

Myth & fact

Myth

“AOD-9604 is fat-burning growth hormone without the side effects.”

Fact

It does not act like GH (no IGF-1 rise, no muscle gain), and in a large trial it did not beat placebo for weight loss.

Combinations

No specific combination notes for this substance yet. The stack check still adds up side effects that several substances share.

Check combinations →

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