Oxymetholone

Anadrol, Anadrol-50, Anapolon, Oxitosona, Androlic, Hemogenin, Drol, A-bombs

Oral steroidsControlled substanceWADA S1.1 · prohibitedEvidence: approved medicine

A potent 17α-alkylated oral steroid derived from DHT and used medically for certain anemias. It carries high liver strain and marked water retention; athletes use it for weight and strength gains.

What it gives

What people use it for and what the sources report. Strength is a general category from the literature: mild, clear or strong.

Purpose

Used for rapid mass and strength gains, especially in strength sports. Medically approved for anemias caused by poor red-cell production and used in HIV wasting; the US brand Anadrol-50 has been discontinued.

What people seek and what studies show

Well studied in medicine. In older men it added 3–4 kg of lean mass, cut trunk fat and raised upper-body strength by about 8–18% versus placebo. In HIV wasting, weight rose by about 3 kg versus 1 kg on placebo, with better appetite and well-being; in dialysis patients muscle mass and grip strength increased. Liver enzymes often rose. Effects at sport doses are known only from users.

Effects

Muscle growthStrength

Evidence: Approved medicine — studied in people for its medical use

Sought effects by goal (as reported)

Mass
Sought for: muscle growth, strength
Recomposition
Sought for: muscle growth
Works against it: water retention / bloating
Strength
Sought for: strength, muscle growth

Possible side effects

Possible does not mean certain: whether they appear depends on dose, duration, individual response and monitoring. Below — what to watch for and how to notice it early.

18 possible side effects

level · how often it is reported
Elevated
Liver strain
Among the most liver-toxic oral steroids: its label has a boxed warning on peliosis hepatis and liver tumors; cholestatic jaundice is reported. Dark urine or itching calls for prompt liver tests.
How to notice: Usually silent early; later tiredness, nausea, itch, dark urine.
common
Elevated
Worse cholesterol (HDL↓ LDL↑)
Its boxed warning also covers atherogenic lipid changes; in a trial in older men HDL fell by about 0.5 mmol/L. The change is silent — only a lipid panel shows it.
How to notice: No symptoms — only visible on a lipid panel.
common
Elevated
Thick blood (hematocrit) / clot risk
Approved to boost red-cell production, so hemoglobin and hematocrit climb; the label asks for regular checks for polycythemia at high doses. Thick blood raises the risk of clots.
How to notice: Often silent; sometimes headaches, flushed face, itch after a hot shower.
common
Elevated
Suppression of natural testosterone & fertility
Strongly suppresses natural testosterone; testicular atrophy and low sperm count are listed on the label.
How to notice: Lower libido and energy, smaller testicles; low natural testosterone on tests after stopping.
In women: Menstrual changes or missed periods, lower libido and energy; reduced fertility.
common
Elevated
Heart strain / heart-muscle thickening
Fluid load, higher blood pressure, thick blood and poor lipids add up; its label warns of edema with heart failure, and a heart attack with clots is reported in a long-term user.
How to notice: Shortness of breath on effort, lower endurance, palpitations.
possible
Elevated
Kidney strain
Rare: severe cholestasis can also damage the kidneys (bile cast nephropathy); in steroid users this has sometimes required dialysis.
How to notice: Usually silent; foamy urine or swelling in later stages.
rare
Moderate
Water retention / bloating
Marked fluid and sodium retention is typical; edema is listed on the label.
How to notice: Puffy face and ankles, softer look, quick weight jumps.
common
Moderate
Higher blood pressure
Fluid and sodium retention commonly raise blood pressure, usually without symptoms; home readings show the trend.
How to notice: Often silent; sometimes headaches, flushing, nosebleeds — a home monitor shows it.
common
Moderate
Black-market quality risk (fakes, contamination)
Pharmacy supply has shrunk; most tablets now come from underground labs with uncertain content.
How to notice: Unexpected effects, pain or infection, a stronger or weaker effect than expected.
common
Moderate
High estrogen (water, gyno risk)
Not aromatized, yet estrogen-like effects occur — possibly via direct estrogen-receptor activation, so aromatase inhibitors may not prevent them.
How to notice: Puffiness, sensitive or itchy nipples, mood swings, water weight.
possible
Moderate
Gynecomastia
Listed on the label even though it is not converted to estrogen; a tender lump under the nipple is an early warning sign.
How to notice: A tender lump or swelling under the nipple.
possible
Moderate
Irritability, aggression, mood swings
As with other potent AAS, irritability, mood swings and aggression can occur; changes others notice are a warning sign.
How to notice: Short temper, irritability, conflicts with others.
possible
Moderate
Androgenic hair loss
DHT-derived; male-pattern baldness is listed on the label.
How to notice: More hair in the shower, thinning at the temples or crown.
possible
MenLow
WomenHigh
Virilization in women (often irreversible)
Strongly virilizing in women: hoarseness, new facial hair and menstrual changes are early signs; voice and clitoral changes may be permanent.
How to notice: Hoarse or deeper voice, new facial or body hair, menstrual changes, clitoral enlargement.
common
Low
Acne, oily skin
Oily skin and acne are common.
How to notice: Oily skin, spots on back, shoulders and face.
common
Low
Nausea, GI upset, pancreatitis risk
Nausea, vomiting and diarrhea are listed; persistent nausea with appetite loss can be an early sign of liver injury.
How to notice: Nausea, fullness, constipation or diarrhea.
possible
Low
Anxiety, insomnia, night sweats
Excitation and insomnia are listed on the label.
How to notice: Trouble falling asleep, night sweats, restlessness.
possible
Low
Insulin resistance / higher blood sugar
Decreased glucose tolerance is listed on the label; it adds to the effect of GH or other drugs that raise blood sugar.
How to notice: Thirst, more hunger, energy crashes after carbs.
possible

What the levels mean

Lowbackground — just be aware
Moderatewatch for signs
Elevatedneeds regular control
Highcritical — can be life-threatening or permanent

Level: general category from the literature, not your personal risk

How often

common
reported often
possible
reported in some people
rare
reported occasionally

How to lower the risks

For 17 of 18 possible side effects there are specific ways to lower the chance: everyday measures, supplements and options a doctor may consider. For the rest — general advice. No measure removes a risk completely. Prescription medicines are listed only for a doctor to decide on, after tests — they have side effects of their own.

ElevatedLiver strain

No alcohol, no other liver stressors, limit oral steroids and their combinations, check liver enzymes.

Measure
Avoiding alcohol and other liver stressorsRegular blood tests
Only if a doctor prescribes
How each option helps (6)
  • Avoiding alcohol and other liver stressors — Removes a major extra liver stressor during oral steroids and other hepatotoxic drugs.
  • Regular blood tests — ALT, AST, GGT and bilirubin show liver strain before symptoms; heavy lifting alone raises AST/ALT for days, and GGT helps tell muscle from liver.
  • Ademetionine (SAMe) — Used for intrahepatic cholestasis in some countries, but trials are small and of low quality; untested in steroid users. Stopping the oral steroid matters most.
  • N-acetylcysteine (NAC) — Restores glutathione; proven in paracetamol poisoning and helped in early acute liver failure of other causes, but untested in steroid users.
  • TUDCA (tauroursodeoxycholic acid) — Improves bile flow in cholestatic disease; in steroid cholestasis only case reports, with failures in severe cases. Stopping the oral steroid matters most.
  • Ursodeoxycholic acid (UDCA) — A doctor may consider it to improve bile flow; in steroid cholestasis benefit is unproven and severe cases often did not respond. Stopping the oral steroid comes first. Has side effects of its own.
ElevatedWorse cholesterol (HDL↓ LDL↑)

Avoid combining several oral steroids; regular cardio, soluble fiber (psyllium), less saturated fat and alcohol; if LDL/ApoB stay high, a doctor may consider a statin. Omega-3 only lowers triglycerides.

Measure
Regular blood testsWorking with a doctorAvoiding alcohol and other liver stressorsRegular cardio training
How each option helps (12)
  • Regular blood tests — A lipid panel with ApoB shows how far HDL has dropped and LDL risen — changes you cannot feel.
  • Working with a doctor — Interprets lipids and ApoB and decides whether a statin or other therapy is warranted.
  • Avoiding alcohol and other liver stressors — Alcohol raises triglycerides; its small HDL bump does not lower heart risk.
  • Regular cardio training — Raises HDL a little and lowers triglycerides; it cannot offset a steroid-driven fall in HDL on its own.
  • Berberine — Placebo-controlled meta-analysis: LDL about 0.5 and triglycerides about 0.4 mmol/L lower; HDL unchanged. Trials are mostly small; no statin substitute.
  • Citrus bergamot — Pooled small trials show lower LDL and triglycerides, but certainty is low to very low; it is no replacement for statins.
  • Omega-3 (fish oil, EPA/DHA) — Clearly lowers triglycerides but does not fix the steroid HDL drop, the main lipid harm; DHA-containing oils may even raise LDL slightly.
  • Psyllium husk fiber — Lowers LDL by about 0.2–0.3 mmol/L (roughly 5–10%), also on top of doctor-prescribed statins; no effect on HDL.
  • Atorvastatin — A doctor may consider it when LDL or ApoB stay high; it strongly lowers them but barely lifts steroid-lowered HDL. Risks: muscle aches, drug interactions, rarely muscle or liver injury. Has side effects of its own.
  • Rosuvastatin — A doctor may consider it when LDL or ApoB stay high; it strongly lowers them but barely lifts steroid-lowered HDL. Risks: muscle aches, rarely muscle or liver injury, slightly higher diabetes risk. Has side effects of its own.
  • Ezetimibe — A doctor may consider it when LDL stays high on a statin or a statin isn't tolerated; it lowers LDL moderately but does not raise HDL. Risks: rare liver-enzyme rises. Has side effects of its own.
  • Pravastatin / pitavastatin (low-interaction statins) — A doctor may consider them when LDL is high and other statins aren't tolerated; they lower LDL moderately and barely lift HDL. Risks: muscle aches, slightly higher diabetes risk. Has side effects of its own.
ElevatedThick blood (hematocrit) / clot risk

Check the blood count regularly; if hematocrit stays high, a doctor decides — usually stopping or reducing the cause, sometimes therapeutic phlebotomy, never blood-bank donation. Avoid dehydration: it thickens the blood further.

Measure
Regular blood testsTherapeutic phlebotomy prescribed by a doctorWorking with a doctor
How each option helps (3)
  • Regular blood tests — A blood count shows hematocrit and hemoglobin climbing toward the range where clot and stroke risk rises.
  • Therapeutic phlebotomy prescribed by a doctor — Only on a doctor's decision, never at a blood bank. Lowers hematocrit quickly but temporarily; repeated sessions drain iron, and a lower clot risk is unproven.
  • Working with a doctor — Manages thick blood by changing what you use or, if justified, by therapeutic phlebotomy.
ElevatedSuppression of natural testosterone & fertility

Check hormones before and after; if they stay low, see an endocrinologist.

Measure
Regular blood testsWorking with a doctor
How each option helps (7)
  • Regular blood tests — LH, FSH and testosterone show how deep suppression is and whether natural production has recovered afterwards.
  • Working with a doctor — Assesses how deep suppression is and guides recovery afterwards, including fertility testing.
  • Clomiphene — A doctor may consider it after stopping, guided by hormone tests; recovery after long use can still take months. Risks: vision changes, mood swings, rare clots. Has side effects of its own.
  • Human chorionic gonadotropin (hCG) — A doctor may consider it to preserve fertility (in men it keeps the testes working); it does not restart the pituitary, so natural LH still has to recover. Risks: higher estradiol, gynecomastia. Has side effects of its own.
  • Tamoxifen — A doctor may consider it after steroids are stopped, guided by hormone tests; it has not been tested for this after steroid use. Risks: blood clots, vision changes. Has side effects of its own. Not offered to women: in the women’s view it adds to a risk this substance already carries.
  • Follicle-stimulating hormone (follitropins, menotropins) — A fertility doctor may consider adding it to hCG when semen tests and FSH stay low; it does not restart the pituitary. Risks: gynecomastia, acne. Has side effects of its own.
  • Toremifene — A doctor may consider it after steroids are stopped, guided by hormone tests; it raised testosterone in subfertile men but was never tested after steroids. Risks: QT prolongation, clots. Has side effects of its own. Not offered to women: in the women’s view it adds to a risk this substance already carries.
ElevatedHeart strain / heart-muscle thickening

Regular cardio, blood pressure control, an echo as a baseline and then yearly.

Measure
Heart screening: ECG and echocardiogramWorking with a doctorHome blood-pressure monitoringRegular cardio training
How each option helps (9)
  • Heart screening: ECG and echocardiogram — Echocardiography shows wall thickening and reduced pumping early, while stopping AAS and treating BP can still help.
  • Working with a doctor — Orders ECG and echocardiography and treats early heart changes.
  • Home blood-pressure monitoring — Keeping BP controlled is one of the main ways to limit heart-wall thickening.
  • Regular cardio training — Supports heart and vessel function, but does not reverse steroid-related heart thickening or weakening.
  • ACE inhibitors (ramipril, perindopril, lisinopril) — Standard treatment for a weak heart (heart failure), and shrinks a thickened heart wall about as well as other BP drugs. Not studied in steroid users; the steroid risk remains. Has side effects of its own.
  • Bisoprolol — In heart failure with weak pumping it lowered deaths in trials; doctors add it to standard therapy. Not studied in steroid users; the steroid risk to the heart remains. Has side effects of its own.
  • Carvedilol — A doctor may add it when tests show weak heart pumping; in heart failure it lowered deaths. Not studied in steroid users, and it does not undo steroid damage. Has side effects of its own.
  • Losartan / valsartan (angiotensin receptor blockers) — In high blood pressure, sartans shrink a thickened heart wall at least as well as other BP drugs. Not studied in steroid users; the steroid risk to the heart remains. Has side effects of its own.
  • Telmisartan — In high blood pressure, ARBs shrink a thickened heart wall at least as well as other BP drugs. Not studied in steroid users; the steroid risk to the heart remains. Has side effects of its own.
ElevatedKidney strain

Drink enough water, control blood pressure, avoid regular painkillers (NSAIDs).

Measure
Fluid & electrolyte managementRegular blood testsWorking with a doctor
How each option helps (6)
  • Fluid & electrolyte management — Good hydration eases kidney stress from heavy training and heat; dehydration plus NSAIDs is a classic cause of acute kidney injury.
  • Regular blood tests — Creatinine reads high in muscular people and with creatine; cystatin C and a urine test give a truer picture of the kidneys.
  • Working with a doctor — Investigates protein in the urine or falling kidney function and can start treatment that slows kidney damage.
  • ACE inhibitors (ramipril, perindopril, lisinopril) — May reduce protein leakage into urine and slow kidney disease. But with dehydration, diuretics or NSAIDs (ibuprofen etc.) they can trigger acute kidney injury. Has side effects of its own.
  • Losartan / valsartan (angiotensin receptor blockers) — May reduce protein leakage into urine. But with dehydration, water cuts, diuretics or NSAIDs (ibuprofen etc.) they can trigger acute kidney injury. Has side effects of its own.
  • Telmisartan — May reduce protein leakage into urine. But with dehydration, diuretics or NSAIDs (ibuprofen etc.) it can trigger acute kidney injury. Has side effects of its own.
ModerateWater retention / bloating

Steady salt and water intake, cardio, check estradiol.

Measure
Working with a doctor
How each option helps (1)
  • Working with a doctor — Tells harmless water retention from swelling due to heart, kidney or liver trouble; steroid labels warn that edema can come with heart failure.
ModerateHigher blood pressure

Less salt, regular cardio, good sleep; home readings; a doctor if it stays high.

Measure
Home blood-pressure monitoringRegular cardio trainingWorking with a doctorAvoiding alcohol and other liver stressors
How each option helps (8)
  • Home blood-pressure monitoring — Seated, rested readings on several days show your true BP; persistently high values are a signal to see a doctor.
  • Regular cardio training — Regular aerobic training lowers resting BP by a few mmHg, more in people with high BP.
  • Working with a doctor — Diagnoses persistent hypertension and prescribes treatment when needed.
  • Avoiding alcohol and other liver stressors — Regular drinking raises blood pressure; cutting it out lowers it.
  • Coenzyme Q10 — Inconsistent: some analyses show a small systolic drop in cardiometabolic disease, but a Cochrane review found no clinically meaningful effect.
  • Magnesium — Meta-analysis of trials: about 2 mmHg lower systolic pressure on average.
  • Omega-3 (fish oil, EPA/DHA) — Small drop of a few mmHg, mainly in people with untreated high blood pressure.
  • Taurine — Meta-analysis of 20 small trials: about 4 mmHg lower systolic pressure on average.
ModerateBlack-market quality risk (fakes, contamination)

Products obtained without a prescription are often fake, mislabeled or non-sterile, and there is no way to check at home. For legal supplements, look for third-party testing (Informed Sport, NSF).

ModerateHigh estrogen (water, gyno risk)

Check estradiol by blood test before acting on symptoms; keep salt and body fat in check.

Measure
Regular blood testsWorking with a doctor
How each option helps (2)
  • Regular blood tests — A sensitive estradiol test shows whether water retention or nipple tenderness really comes from high estrogen.
  • Working with a doctor — Prescription estrogen control is safer when adjusted by lab results than by guesswork.
ModerateGynecomastia

React early: see a doctor at the first lump, check estradiol and prolactin.

Measure
Working with a doctor
How each option helps (1)
  • Working with a doctor — Early assessment of breast-tissue growth allows treatment before the change becomes permanent.
ModerateIrritability, aggression, mood swings

Good sleep, fewer stressors, tell someone close to you what to watch for.

Measure
Avoiding alcohol and other liver stressorsSleep hygiene
How each option helps (2)
  • Avoiding alcohol and other liver stressors — Alcohol and other drugs on top of steroids explain much of the link between steroid use and violence.
  • Sleep hygiene — Enough sleep lowers irritability and improves impulse control.
ModerateAndrogenic hair loss

Ketoconazole shampoo, minoxidil, a dermatologist early if you are prone to it.

Supplement or OTC product
How each option helps (1)
  • Minoxidil (topical) — Slows thinning and regrows some hair; scalp itching and early temporary shedding are common, unwanted facial hair possible. Gains fade once stopped.
MenLow
WomenHigh
Virilization in women (often irreversible)

Stop at the first voice change and see a doctor — early stopping matters.

Measure
Working with a doctor
How each option helps (1)
  • Working with a doctor — Steroid labels say to stop at the first mild signs (hoarse voice, facial hair, clitoral growth) to prevent permanent change; checks catch them early but do not make use safe.

Low-level side effects

Acne
Gentle skin care, cleansing after training, a dermatologist if it spreads.
Supplement or OTC product
How each option helps (3)
  • Adapalene — Reduces spots in many users. Redness, scaling, dryness and stinging are common early and usually ease; acne may look worse at first. Rarely, allergic swelling.
  • Benzoyl peroxide — A first-line acne option. Dryness, redness and peeling are common at first; it bleaches hair and fabric; rarely, serious allergic reactions. Severe steroid acne needs a dermatologist.
  • Zinc — Trials show a modest drop in inflamed spots, weaker than antibiotics; steroid acne is driven by androgens.
Digestion
Smaller meals, enough fluid and fiber; a doctor for severe abdominal pain.
Measure
Working with a doctor
Supplement or OTC product
How each option helps (2)
  • Working with a doctor — Assesses persistent vomiting or severe belly pain (possible pancreatitis or gallstones) and adjusts prescribed GLP-1 treatment when nausea persists.
  • Pancreatin + dimeticone (Pankreoflat) — May ease heaviness and gas after meals; can cause nausea or diarrhea. Not for pork or cow's milk protein allergy (anaphylaxis reported) or early acute pancreatitis.
Sleep & anxiety
Sleep routine, no stimulants late in the day, magnesium or melatonin.
Measure
Sleep hygiene
Supplement or OTC product
How each option helps (5)
  • Sleep hygiene — A steady routine and no late caffeine ease stimulant- and steroid-related insomnia; night sweats on trenbolone persist regardless.
  • Glycine — Small trials show slightly better sleep quality and less next-day fatigue; not a sedative and not for anxiety.
  • L-theanine — Small gain in subjective sleep quality; effects on anxiety are inconsistent. May smooth caffeine jitters but won't offset strong stimulants like clenbuterol.
  • Magnesium — Three small, low-quality trials in older adults: falling asleep about 17 minutes sooner. No good data in athletes.
  • Melatonin — Helps you fall asleep a little faster, especially with a shifted body clock; does not treat anxiety or night sweats.
Blood sugar
More daily movement, fewer fast carbs, check fasting glucose and HbA1c.
Measure
Glucose monitoringRegular blood testsRegular cardio trainingWorking with a doctor
How each option helps (7)
  • Glucose monitoring — Rising fasting readings reveal insulin resistance from GH or other drugs early.
  • Regular blood tests — Fasting glucose, insulin and HbA1c catch rising blood sugar early — key with GH, its secretagogues and insulin.
  • Regular cardio training — Improves insulin sensitivity — useful against the blood-sugar rise from GH and its secretagogues.
  • Working with a doctor — Interprets glucose markers and treats early metabolic problems.
  • Berberine — Meta-analyses: lower fasting glucose and HbA1c (about 0.6% in type 2 diabetes); smaller effect when glucose is normal.
  • Alpha-lipoic acid — Small drops in fasting glucose, insulin and HbA1c in meta-analyses; no real counter to GH- or insulin-driven resistance.
  • Psyllium husk fiber — Slows sugar absorption: lower fasting glucose and HbA1c, mostly in people with diabetes.

Check-ups and blood tests

Which tests and check-ups to do and when. This is a guide — agree the exact schedule with your doctor.

Baseline tests
your own starting values — every later result is compared with them
Lipid panel (HDL, LDL, triglycerides, ApoB)cholesterol
Liver panel (ALT, AST, GGT, bilirubin)liver
Complete blood count (hematocrit, hemoglobin)hematocrit
Kidney panel (creatinine, eGFR, cystatin C)kidneys, blood pressure
Fasting glucose, insulin, HbA1c
Electrolytes (potassium, sodium, magnesium)water retention
Testosterone (total, free), LH, FSH, SHBGnatural testosterone
Estradiol (sensitive assay)high estrogen, gynecomastia
Prolactingynecomastia
Home blood-pressure logheart, kidneys, blood pressure, water retention
ECGheart
Echocardiogram (heart ultrasound)heart
Urinalysiskidneys
While taking
about 4–6 weeks in, then every 6–8 weeks — agree the exact schedule with your doctor
Lipid panel (HDL, LDL, triglycerides, ApoB)cholesterol
Liver panel (ALT, AST, GGT, bilirubin)liver
Complete blood count (hematocrit, hemoglobin)hematocrit
Kidney panel (creatinine, eGFR, cystatin C)kidneys, blood pressure
Fasting glucose, insulin, HbA1c
Electrolytes (potassium, sodium, magnesium)water retention
Estradiol (sensitive assay)high estrogen, gynecomastia
Prolactingynecomastia
Home blood-pressure logheart, kidneys, blood pressure, water retention
Urinalysiskidneys
After stopping
4–8 weeks after stopping (later after long-acting injections), then until values return to baseline
Lipid panel (HDL, LDL, triglycerides, ApoB)cholesterol
Liver panel (ALT, AST, GGT, bilirubin)liver
Complete blood count (hematocrit, hemoglobin)hematocrit
Kidney panel (creatinine, eGFR, cystatin C)kidneys, blood pressure
Fasting glucose, insulin, HbA1c
Testosterone (total, free), LH, FSH, SHBGnatural testosterone
Semen analysisnot earlier than 3 months after stopping, then every 3 months until normalnatural testosterone
Every year
with regular or repeated use
ECGheart
Echocardiogram (heart ultrasound)heart

Which doctors can help

Sports physiciancoordinates everything
Cardiologistcholesterol, hematocrit, heart, blood pressure
Endocrinologistnatural testosterone, high estrogen, gynecomastia
Gastroenterologist / hepatologistliver
Nephrologistkidneys
Psychotherapist / psychiatristmood
Dermatologisthair loss
Gynecologistvirilization, natural testosterone (women)

At home

  • Home blood pressure: 2–3 times a week in the morning, keep a log

Get medical help at once if

  • Swelling, pain or redness in one leg; sudden shortness of breath or chest pain; sudden one-sided weakness or numbness, trouble speaking or seeing — seek urgent care.
  • Chest pain or pressure, breathlessness on light effort, swollen ankles, fainting — seek urgent care.
  • Yellow skin or eyes, dark urine, pale stools, intense itching, pain under the right ribs — see a doctor now; sudden severe abdominal pain with dizziness or fainting — call emergency services.
  • Much less urine than usual, cola-colored urine, new swelling, flank pain — see a doctor now.
  • A painful lump under the nipple or nipple discharge — see a doctor early, while it can still regress; a hard, painless or fixed lump, skin dimpling or bloody discharge — see a doctor promptly.
  • Sudden severe headache, vision changes, numbness or weakness on one side, trouble speaking — call emergency services.
  • Rapid weight gain with breathlessness, or swelling of one leg — see a doctor promptly.
  • Losing control of anger, thoughts of harming yourself or others — stop and get help today.
  • Deepening voice, new facial hair, clitoral enlargement — stop and see a doctor: changes can become permanent. (women)

In an emergency, call your local emergency number.

For women

Strongly androgenic for women: voice deepening, facial hair, clitoral enlargement and menstrual disruption are common; voice and clitoral changes may be permanent. Its liver and lipid risks apply equally to women.

Myth & fact

Myth

“Anadrol doesn't aromatize, so it can't cause estrogen-type side effects.”

Fact

It isn't converted to estrogen, yet water retention and gynecomastia are well known and listed on its label; the mechanism is still debated.

Combinations

Overlap5α-reductase inhibitor with steroids it cannot affect

DHT-derived steroids, trenbolone and trestolone act without 5α-reductase, so finasteride and dutasteride do not lower their effect on hair or prostate; they only reduce DHT made from testosterone, while finasteride and dutasteride keep their own side effects.

DrostanoloneMetenolone1-TestosteroneOxandroloneStanozololMesteroloneMethasteroneTrenboloneTrestoloneMethyl-1-testosterone (M1T)Desoxymethyltestosterone (DMT, Madol, Pheraplex)Epistane (methylepitiostanol, Havoc)ProstanozolMestanoloneStenbolone1-Andro (1-androsterone) and related prohormonesEpiandrosterone (Epi-Andro)Androstanolone (dihydrotestosterone, DHT)

Check combinations →

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